J. B. Huffman, master stonemason, designed and built this house in 1914. He lived here until 1919, when he began construction on another residence next door (see 2223 Lipscomb Street). The house was rented out until 1929, then sold to attorney William Pannill, whose family lived here until 1974. Pannill was a partner with John Miner in the firm of Hiner & Pannill, attorneys for several oil companies. The walls are of ashlar construction, with dressed blocks of Pecos red sandstone laid in regular courses. A full porch with Tuscan columns extends across the front. As an excellent example of stone construction by a master craftsman, the house appears to be eligible for the National Register. The Huffman-Pannill House is a contributing resource in the Fairmount-Southside Historic District (local and national).
