The Tripplehorn House is a two-story wood-framed L-plan structure with a veneer of shingles. A porch is set in the angle of the wings. A loggia wing extends forward, flanked by a driveway leading to a porte-cochere. All roofs are low-pitched hips. Built c. 1910 for Frank V. Lanham, the house was owned for several years by Robert L. Fowler, a prominent oilman, before being sold to the Tripplehorn family, also prominent in the oil industry. The family still owns the house. It is an excellent example of a Prairie Style residence and would appear to be eligible for the National Register. It is the last remaining house on a large block that has been cleared for the expansion of a nearby hospital. The Tripplehorn House was demolished for the expansion of the All Saints Hospital (now Baylor-All Saints).